Background/Objective: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder characterized by hepatocyte teatosis. The prevalence of this disorder in general population screening with ultrasonography ranging from 13% to 23%. According to many studies, NAFLD is related to obesity, diabetes mellitus, dyslipidemia, and metabolic syndrome.The aim of this study was ultrasound screening of nonalcoholic fatty liver in Isfahan MEDICAL university PERSONNEL.
Patients and Methods: According a general announcement to office PERSONNEL of Isfahan University of MEDICAL Sciences, a total of 199 volunteers enrolled in this study. Cases underwent: 1) liver and spleen ultrasonography (3.5 MHZ probe -HS2000 Honda electric equipment), and 2) biochemical tests: FBS, LFT, fasting Cholesterol and fasting triglyceride. Liver steatosis was graded on the basis of abnormally intense, high level echoes as explained by paoulekar G.
Results: Biochemical and anthropometric characters are; Mean Age: 43.1±4 Years, F/M ratio: 97/102, BMI: 26.1±5, Hypercholesterolemia: 37%, Hypertriglyceridemia 56%, SGPT>36: 21%, SGOT>34: 12%, FBS: 94.5±31, NAFLD: 52.8%. 51%, 34.6% AND 14.4% of NAFLD were grades 1 to 3 respectively. There was association between SGPT, BMI, and triglyceride with NAFLD. Splenic span and portal vein diameter were significantly higher in NAFLDs than others were. (but not about liver span).
Conclusion: In the present study, prevalence of NAFLD is too high, life style abnormalities or genetic factors should be considered.